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Developing cells, like humans, shut many doors to pursue their career
Developing cells, like humans, shut many doors to pursue their career
Red blood cells close more doors than most by degrading their nucleus
Janice Carr-Centers for Disease Control and Prevention
Like greyhounds before a race, key genes in stem cells are primed for activity and simultaneously held back
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Fickle and flexible
Pursuing your dream career can be a rather depressing experience. As you progress through school, you increasingly narrow the number of subjects you study, shutting doors to other paths even as you follow your long-held ambitions. Oddly enough, this is something you have in common with the cells in your body. As you developed from an embryo, they made a series of decisions to follow a particular developmental path to become, say, a nerve cell or a liver cell. And once they had specialised into their final cell type, there was no going back.