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The active process of gene expression, known as transcription, does not occur homogenously throughout the cell nucleus but occurs in discrete regions called transcription factories. These sites are highly enriched in specialized enzymes and protein complexes that are needed to turn genes on. Peter’s research has shown that multiple genes can share the same transcription factory and suggests that individual genes are continually moving into and out of these sites, while simultaneously switching on and off. Peter has been studying how genes and distal regulatory elements interact and how these complexes engage other gene complexes in transcription factories.